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Tag: biotechnology

Stroke Cats Happily and Stay Away from Allergies

For cat lovers, the most tragic thing is probably the cat allergy. As soon as you get close to the cat, you sneeze, have a runny nose, or itchy eyes, skin rashes, and even asthma attacks. There are many people who are allergic to cats, with about 1 in 10 in the population. In some areas, as many as 30% of the population are allergic to cats….

Ornithine Aminotransferase is a New Target for Pancreatic Cancer Treatment with Fewer Side Effects

Pancreatic cancer (PC), a highly malignant tumor of the gastrointestinal tract, is difficult to diagnose and treat, with pancreatic ductal adenocarcinoma (PDAC) accounting for more than 95% of all pancreatic cancers. In recent years, the incidence of pancreatic cancer has increased significantly. It is often diagnosed at an advanced stage due to its low early diagnosis rate. With its low survival rate and poor prognosis,…

Novel Therapies Based on Small-Molecule Antibodies Hold Immense Promise

Antibodies, the extraordinary proteins that serve as the frontline troops of the human immune system, have recently gained attention for their ability to combat tiny compounds known as haptens. Because of their small size, these elusive targets present particular difficulty for the immune system to identify as foreign invaders. However, researchers’ inventiveness has resulted in the creation of several techniques to bypass this barrier and…

Half-Life Strategies in Supporting the Development of Protein Therapeutics

Therapeutics based on macromolecular proteins and peptides have successfully been efficiently applied to treat serious human diseases. With the development of biotechnologies, a great number of authorized protein therapeutics and drug products have been utilized in clinical research over the last few decades. However, the main issue that needs to be resolved currently for protein therapeutics is the short half-lives caused by fast degradation in serum and quick elimination during clinical application due to enzymatic…

Potential Treatment Strategies for CNS Diseases Require More Research

For several decades, CNS diseases have caused serious burdens for individuals with these diseases in both physical and mental health. Studies show that more than 95% of CNS diseases have an unknown etiology, which presents scientists with significant obstacles on the road to the creation of efficient treatments. Parkinson’s disease and Alzheimer’s disease are the two most common types of conditions in the group of…

Summer’s Invisible Killer—Mosquitoes

As summer unfolds in the year 2023, people will contend with not only scorching temperatures but also the constant annoyance of mosquitoes buzzing around and biting at every opportunity. The combination of high temperatures and factors such as food spoilage creates an ideal breeding ground for mosquitoes, making them a prominent threat during the summer months. But why are mosquitoes considered the killers of summer?…

Scarless Wound Healing Achieved Through Stem Cell-Derived Exosomes

The journey of the human body begins in infancy, often marked by flawless perfection. However, as time elapses and individuals grow, the passage of time become evident on their skin. From minor mosquito bites to major surgical incisions or burns, wounds of varying sizes leave enduring marks on the body. While some wounds heal swiftly, leaving no visible trace, others persist over the years, giving…

Advancing Cancer Therapy: The Revolutionary Impact of Bispecific Antibodies

In the ever-evolving field of biomedical research, a significant transformation is underway in the realm of tumor treatment. The emergence of Bispecific Antibodies (BsAbs) is marking a groundbreaking shift, positioning itself as a revolutionary cornerstone in the ongoing battle against cancer. Bispecific antibodies, a class of antibodies with the unique ability to simultaneously bind to two distinct antigens, represent a paradigm shift in the approach…

Combination of intramuscular and intranasal mRNA vaccination induces more lung-resident memory T cells

In response to COVID-19 outbreaks, mRNA vaccine technology has been rapidly developed and successfully applied. the standard method of immunization with the SARS-CoV-2 mRNA vaccine consists of two intramuscular injections of immunization at 21 or 28 days intervals, followed by a booster immunization several months later. Advantages of mRNA vaccines include: * Strong immunogenicity against CD8+ T and CD4+ T cells * No carrier immunity, allowing…