The Comfort Inn Charleston Hotel is a great place to relax and unwind. comfortinncharleston.com

The Comfort Inn Charleston is the ideal location for exploring all that historic Charleston. Our hotel is immediately close to MUSC Children’s Hospital, in the heart of the Medical District. We’re also just a few blocks from Charleston’s world-famous historic area, which features numerous 18th-century buildings. The Medical University of South Carolina, College of Charleston, historic Fort Sumter, and famous carriage, strolling, and bus tours are within a mile of the hotel.